Interlaboratory Comparison Investigations (ICIs) for human biomonitoring of chromium as part of the quality assurance programme under HBM4EU

Stefanie Nübler,Moritz Schäfer,Karin Haji-Abbas-Zarrabi,Stefan Marković,Katarina Marković,Marta Esteban López,Argelia Castaño,Hans Mol,Holger M Koch,Jean-Philippe Antignac,Jana Hajslova,Cathrine Thomsen,Katrin Vorkamp,Thomas Göen

Journal of Trace Elements in Medicine and Biology（2022）

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摘要

•HBM4EU QA/QC programme for high interlaboratory comparability of chromium analysis.•Interlaboratory comparison investigations (ICI) of chromium in urine, plasma, blood.•ICP-MS and EAAS appropriate for determination of occupational levels of chromium.•Improvement of analytical methods recommended for lower LOQs in Cr analyses.•European network for chromium analysis in 18 countries supports in risk assessment.

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关键词

Chromium,HBM4EU,Occupational exposure,Urine,Plasma,Red blood cells,Whole blood,Human biomonitoring (HBM),Interlaboratory comparison investigation (ICI),Inductively coupled plasma mass spectrometry (ICP-MS),Electrothermal atomic absorption spectrometry (EAAS)

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