Behavioral markers of social anxiety in Cornelia de Lange Syndrome: A brief systematic review
Journal of Affective Disorders(2022)
Abstract
•Individuals affected by Cornelia de Lange Syndrome (CdLS) are at increased risk of social impairments.•Social impairments in CdLS are characterized by social anxiety, selective mutism, extreme shyness that show an upward trend with age and IQ and exhibit only partial overlappings with autistic features.•Fine-grained behavioral observation of structured social interactions is the most suitable method to detect social anxiety indicators in syndromic individuals with intellectual disabilities.•Longitudinal studies are needed to explore age-related features of social anxiety among CdLS individuals.
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Key words
Cornelia de Lange Syndrome,Social anxiety,Social impairments,Genetic syndromes comparisons
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