高通量测序技术在确认病原微生物中存在的问题与挑战
Chinese Journal of Clinical Laboratory Science(2021)
Abstract
通过宏基因组二代测序(metagenomic next-generation sequencing,mNGS)技术确认病原微生物已成为新发、突发、罕见及常规检测阴性的感染性疾病诊断的重要手段,这项技术提高了临床对感染性疾病的认识,成为精准诊疗的重要驱动力.该文就mNGS在临床应用中的问题展开讨论.
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