宫颈组织免疫组化染色检测P16/Ki67的表达在LSIL和ASC-US中的应用价值

Journal of Modern Laboratory Medicine(2021)

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Abstract
低级别鳞状上皮内病变(low-grade squamous intraepithelial leasion,LSIL)和非典型鳞状细胞(atypical squamous cells of undetermined significance,ASC-US)是宫颈病变的常见类型,临床上主要采用HPV-DNA检测对LSIL和ASC-US进行分流,但该分流方法 存在漏诊率高等问题.目前,迫切需要一些生物标记物和检测方法 来预测LSIL和ASC-US病例的转归,实现其分流管理.
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