mTOR调控自噬参与糖尿病并发症的研究进展
Basic & Clinical Medicine(2021)
Abstract
在糖尿病状态下,失调的自噬可能导致多个脏器的病变.mTOR介导的自噬参与糖尿病并发症及合并疾病的调控机制,如糖尿病肾病、非酒精性脂肪肝、糖尿病心脏病、糖尿病性视网膜病变、糖尿病周围神经病变等.对糖尿病自噬机制的研究将有助于发现新的治疗靶点,更好的预防和治疗糖尿病并发症.
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Key words
mtor|autophagy|new hypoglycemic drugs|diabetic complications
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