上皮间充质转化与呼吸系统疾病研究进展
The Journal of Medical Theory and Practice(2021)
Abstract
上皮间充质转化(Epithelial-mesenchymal transition,EMT)是指上皮细胞逐渐失去其原有的特性和功能,并获得间质细胞表型的过程.EMT在肺发育和许多肺部疾病如慢性阻塞性肺疾病、肺癌和肺纤维化中起着重要作用.本文介绍了EMT的形态学变化和潜在的分子机制,并讨论了它如何有助于慢性肺疾病的发病机制和存在的争议.
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