转录组测序描绘血液肿瘤融合基因图谱
Journal of Leukemia and Lymphoma(2021)
Abstract
近年来转录组测序(RNA-seq)技术的成熟和推广应用,为直接测序和鉴定各种可能发生的融合转录本提供了强大工具。随着大宗病例RNA-seq研究报道的增多,血液肿瘤中融合基因的真实图谱日渐清晰。文章结合第62届美国血液学会年会的报道对相关研究进展进行介绍。
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Key words
Hematological neoplasms,Transcriptome,Gene sequencing,Fusion genes
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