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Neurodegeneration and neoangiogenesis in the cerebellar cortex in pentylenetetrazol (PTZ)- kindled rats treated with axitinib and rapamycin

Leonid Godlevsky,Mykhailo Pervak,Olesya Poshyvak,Kirill Latypov,Kseniya Prybolovets

JOURNAL OF THE NEUROLOGICAL SCIENCES（2021）

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Abstract
Morphological changes induced in pentylenetetrazol (PTZ)-kindled rats create the basis for the resistance of chronic brain epileptization. Cerebellar contribution to kindling seizures development was shown (Godlevsky L.S.et al., 2020). To investigate histological characteristics of the cerebellar paleocortex in PTZ-kindled rats under conditions of axitinib and rapamycin administration.
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Key words
cerebellar cortex,pentylenetetrazol,neoangiogenesis,axitinib
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