SHARP Syndrome

Sanogo A,Diaby LM,B Berthe,Kane AST,Malle Mamadou,Traore D,Traore A, Dembele IA,Sylla O,Fofana Y,Kaya Assetou Soukho,Abdel Kader Traore

Pediatrie pro praxi（2021）

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Abstract

Sharpov syndrĂłm (mixed connective tissue disease - MCTD) je zriedkavĂŠ autoimunitnĂŠ ochorenie spĂĄjajĂşce klinickĂŠ prĂznaky systĂŠmovĂŠho lupusu, systĂŠmovej sklerĂłzy, polymyozitĂdy a reumatoidnej artritĂdy. Variabilita klinickĂ˝ch prejavov Äasto odÄaÄžuje sprĂĄvnu diagnĂłzu. DemonĹĄtrujeme kazuistiku 11-roÄnej pacientky s diagnĂłzou Sharpov syndrĂłm. Poukazujeme na dĂ´leĹžitosĹĽ imunofluorescenÄnĂŠho vyĹĄetrenia s dĂ´kazom antinukleĂĄrnych protilĂĄtok s ich ĹĄpecifikĂĄciou v diagnostike ochorenia. VzhÄžadom na ĹĄirokĂŠ spektrum klinickĂ˝ch prejavov je nevyhnutnĂĄ medziodborovĂĄ spoluprĂĄca.

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syndrome

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