HTSDSF Explorer, A Novel Tool to Analyze High-throughput DSF Screenings
Journal of Molecular Biology（2022）
Abstract
•A high-throughput focused DSF data analyzer, which runs very fast and in a highly efficient manner.•The software integrates plate-screening with protein–ligand affinity calculations.•Provides a Rank of all binders ordered according to differences in melting temperatures.•Generates Excel files and final KD reports automatically.
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Key words
high-throughput compound screening,thermal shift assay,differential scanning fluorimetry,automatic Tm,automatic KD analysis
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