Infant and Child health status ahead of implementation of an integrated intervention to improve nutrition and survival: A difference-in-difference quasi-experimental baseline assessment

Abstract Background Burundi has one of the poorest child health outcomes in the world. With an acute malnutrition rate of 5% and a chronic malnutrition rate of 56%, under five death is 78 per 1000 live births and 47 children in every 1000 children will not celebrate their first birthday. In response, Village Health Works, a Burundian-American organisation has invested in an integrated clinical and community intervention model. Ahead of implementation of this initiative, we conduct a baseline assessment using a difference-in-difference design in an effort to measure incremental effects. Methods A quasi-experimental evaluation design (difference-in-difference) was employed. Adopting the methodology of the DHS, a sample of 952 and 990 households comprising of 2675 and 3311 birth histories respectively in the treatment and control areas were reached. Mortality data were analysed with R package for mortality computation, Complex Samples Module of IBM – SPSS for other outcomes and Emergency Nutrition Assessment software for nutrition data. Logistic regression was used to assess strength of associations and cox regression model for assessing risk of mortality Results The incidence of low birth weight (LBW) was 5.7% at the program area compared to 7.2% at the controlled area with the strongest predictor being malnourished women (OR 1.4 95%CI 1.2 – 7.2 p=0.043). Fever incidence was higher in the program area (50.5%) in comparison to 48.4% in the control. Non-consumption of minimum acceptable diet was significantly associated with fever (OR 1.67 95%CI 1.07 – 2.61). Acute and chronic malnutrition was 7.6% and 45.8% respectively with non-receipt of Vitamin A was significantly associated with chronic malnutrition. Under-five mortality rate was 32.1 per 1000 live births in the program area and 33.6 in the control. Infant mortality rate was 25.7 in program area and 20.4 in the control. Risk of under-five mortality was higher in the neonatal period (HR 20.72 95% 8.64 – 49.65 p=0.001). Conclusion Improving child health status is complex and therefore investing into an integrated intervention yields best results. Given that the risk of all under-five was higher at the neonatal period, strengthening the health system to provide quality care is crucial.