A review of antituberculosis drugs emphasising on phytotherapeutic aspect

The long duration tuberculosis therapy makes causes several serious side effects, hepatotoxicity being the main. Hepatotoxicity is the most serious adverse effect related to tuberculosis treatment which interrupts the successful completion of tuberculosis treatment antioxidant system of the body effectively neutralises reactive oxygen species formed during the normal metabolic process. Any imbalance in this neutralization process causes oxidative stress leading to causation of various diseases. Research has enabledthe use of several medicinal plants from time to time to treat toxic manifestations from various toxigenic substances. This review is aimed to provide an insight for the phytotherapeutic intervention of the medicinal plants for the effectiveness of the existing tuberculosis therapy.