Mechanisms of allergy/immunology Shared DNAmethylation signatures in childhood allergy: The MeDALL study

Cheng-Jian Xu, PhD,* Olena Gruzieva, MD, PhD,* Cancan Qi, MSc, Ana Esplugues, PhD, Ulrike Gehring, PhD, Anna Bergstr€ om, PhD, Dan Mason, PhD, Leda Chatzi, MD, PhD, Daniela Porta, MSc, Karin C. Lodrup Carlsen, MD, PhD, Nour Ba€ız, PhD, Anne-Marie Madore, PhD, Harri Alenius, PhD, Bianca van Rijkom, BSc, Soesma A. Jankipersadsing, MSc, Pieter van der Vlies, BSc, Inger Kull, PhD, Marianne van Hage, MD, PhD, Mariona Bustamante, PhD, Aitana Lertxundi, PhD, Matias Torrent, MD, PhD, Gillian Santorelli, MSc, Maria Pia Fantini, MD, Vegard Hovland, MD, PhD, Giancarlo Pesce, PhD, the BIOS Consortium, Nanna Fyhrquist, PhD, Tiina Laatikainen, MD, PhD, Martijn C. Nawijn, PhD, Yang Li, PhD, Cisca Wijmenga, PhD, Mihai G. Netea, MD, PhD, Jean Bousquet, MD, PhD, Josep M. Anto, MD, PhD, Catherine Laprise, PhD, Tari Haahtela, MD, PhD, Isabella Annesi-Maesano, MD, PhD, Kai-H akon Carlsen, MD, PhD, Davide Gori, MD, PhD, Manolis Kogevinas, MD, PhD, John Wright, FRCP, Cilla S€ oderh€ all, PhD, Judith M. Vonk, PhD, Jordi Sunyer, MD, PhD, Erik Mel en, MD, PhD, and Gerard H. Koppelman,MD, PhD Groningen, Nijmegen, Utrecht, and Metslawier, The Netherlands; Hannover, Bonn, and Berlin, Germany; Stockholm, Sweden; Val encia, Madrid, Barcelona, Bizkaia, Leioa, Donostia-San Sebastian, Balearic Islands, and Menorca, Spain; Bradford, United Kingdom; Los Angeles, Calif; Rome and Bologna, Italy; Oslo, Norway; Paris and Montpellier, France; Qu ebec City and Saguenay, Qu ebec, Canada; and Helsinki and Kuopio, Finland