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Gold-Catalyzed Amide-Alkynes Oxidation/Carbene/Alkyne Metathesis: Access to Functionalized γ-Lactams

W. Shen,Yi Zheng, Ting Zhang

Organic & Biomolecular Chemistry（2021）

Cited 7|Views0
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Abstract
An efficient gold-catalyzed oxidative cyclization of amide-alkynes is developed. A series of functionalized γ-lactams are easily accessed by employing this strategy. The tandem reaction proceeds through alkyne oxidation, carbene/alkyne metathesis,...
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