Vmrr_a_289721 1..6

1Unit of Biomedical Science, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia; 2Department of Veterinary Epidemiology and Public Health, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia; 3Department of Clinical Medicine, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia; 4Department of Paraclinical Studies, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia Abstract: Brucellosis is an infectious and widespread zoonotic disease caused by bacteria of the genus Brucella and can induce considerable human suffering and huge economic losses in animals. Thus, the aim of this study was to conduct a systematic review and meta-analysis on the seroprevalence of bovine brucellosis in Ethiopia. PubMed, Science Direct, African Journals Online, and Google Scholar were used to search the articles. All references were screened and articles, which reported seroprevalence of bovine brucellosis in Ethiopia were included in the study. Meta-analysis using random-effects models was made to calculate the pooled seroprevalence of brucellosis. This review included 15 papers. The estimated pooled seroprevalence of brucellosis was found to be 3.0% (95% CI: 2.0, 4.0). The subgroup analysis showed that there was a statistically significant association between the disease and geographical location, setting, laboratory technique employed and study years. Also, there was some evidence of publication bias (Egger’s test, p = 0.0003) on studies reporting the prevalence of brucellosis in Ethiopia. This review proves a high seroprevalence of brucellosis in the country and appropriate control strategies are recommended. Moreover, further study on the risk factors is also required to develop cost-effective preventive strategies.