Evidence of maternal vascular malperfusion in placentas of women with congenital heart disease.

Ana E Rodríguez-Soto,Donna Pham, Tracy Tran,Morgan Meads,Valentina Stanley,Dora Melber,Leah Lamale-Smith,Kathy Zhang-Rutledge,Rebecca Rakow-Penner,Laith Alshawabkeh,Mana M Parast,Francisco Contijoch

Placenta（2021）

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摘要

•Women with congenital heart disease (CHD) deliver small babies and placentas.•Maternal CHD was associated with a high prevalence of pre-eclampsia.•Their placentas have evidence of maternal vascular malperfusion and no vasculopathy.•Cardiovascular dysfunction due to CHD may impact placental development and consequently fetal growth.

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