Physiopatological aspects of covid-19 in humans

In December 2019, the largest epidemic associated with a Coronavirus began, SARS-CoV-2 (better known as COVID-19, or Coronavirus Disease / 2019). The first focus was in Hubei province, China, and since then it has spread throughout the world, reaching, until April 2020, almost 2.8 million people and approximately 193 thousand deaths worldwide. The agent causes respiratory, hemodynamic, digestive and inflammatory disorders, which can lead to death in any individual, although the lethality rate is higher in individuals over 60 years and with some comorbidity, such as diabetes or previous cardiac problems. The present study describes the pathogenesis of the agent and the anatomopathological lesions induced by COVID-19 in humans.