Research Paper: Protective Effects of Pelargonium graveolens Essential Oil on Methomyl-Induced Oxidative Stress and Spatial Working Memory Impairment in Association with Histopathological Changes in the Hippocampus of Male Wistar Rats

* Corresponding Author: Khene M’hammed Amine, PhD. Address: Laboratory of Animal Physiology and Cell Signaling, ENS Kouba, Algiers, Algeria. Tel: +213 (77) 8536367 E-mail: amine.khene@gmail.com Introduction: Methomyl (MET) is a carbamate insecticide, used in agriculture and public health to eliminate harmful insects. Besides its advantages in agriculture, it causes neurotoxic effects. The aim of this study was to evaluate the effect of MET on Spatial Working Memory (SWM), oxidative stress parameters, and histopathological changes in the hippocampus, as well as the possible protective role of Pelargonium graveolens Essential Oil (EO).