Evaluation of anti-urolithiatic activity of cascabela thevetia

This experiment was conducted to evaluate the anti-urolithiatic potential of Cascabela thevetia leaves on experimentally produced calcium oxalate crystals. Maceration process was used for the extraction process in which the resultant extract was then heated on water bath to make semisolid and then refrigerated in air tight container for further use. Methanolic fraction of the leaves of C. thevetia was found to have anti-urolithiatic property but is lower when compared with the standard (cystone). It has shown efficiency in the dissolution of calcium oxalate crystals. In-vitro studies have shown a positive response to the anti-urolithiatic activity and further in-vivo studies are warranted for further investigations.