Nanoparticles-Based Novel Drug Delivery System: A Review

For the past few years, there has been a considerable research on the basis of Novel drug delivery system, using particulate vesicle systems as drug carriers for small and large molecules. Nanoparticles, Liposomes, Microspheres, Niosomes, Pronisomes, Ethosomes, Proliposomes have been used as drug carrier in vesicle drug delivery system. Various polymers have been used in the formation of Nanoparticles. Nanoparticles have been improving the therapeutic effect of drugs and minimizing the side effects. Basically, nanoparticles have been prepared by using various physical, chemical, mechanical and biological techniques. Nano-medicines have been particularly used for cell repair, antimicrobial techniques, anticancer therapy, gene delivery system, vector cell repair, nano-robot for chromosome repair therapy etc. Sometimes, nanoparticles are likely to be unsafe for the biological system. Nanoparticles have been evaluated by using parameters of drug entrapment efficiency, particle shape, drug release study.