Risk factors analysis of HPS patients with acute Stanford A aortic dissection

Background: AAD refers to the blood flow into the middle membrane through the intimal rupture of the aorta. HPS is a common complication of Stanford-A AAD. The risk factors of HPS are remaining unclear Methods: In this study, we have probed the potential risk factors of hepatopulmonary syndrome (HPS) patients with acute Stanford A aortic dissection. 18 HPS patients with acute Stanford A aortic dissection were selected as case group. 36 Normal people were considerate as control group. Demographic data, treatment methods, AD related disease history, clinical symptoms and Charlson comorbidity index (CCI) values of each patient were collected. Meanwhile, the values of maximum diameter of ascending aorta (mm), aortic dissection range, and main branch of aorta, pleural effusion/blood, and pericardial effusion/blood were measured by two experienced cardiovascular radiological physicians. Univariate and multivariate conditional logistic regression analysis were used in this study. Results: CCI value and the branches of the brachiocephalus in case group were significant higher than that in control group (p<0.05). Univariate conditional logistic regression analysis showed CCI and branches of the brachiocephalus were associated with HPS. Multivariate conditional logistic regression analysis suggested that branches of the brachiocephalus was an independent risk factor for HPS (OR=7.02, 95%CI=1.28-38.62, p=0.025). Conclusions: Branches of the brachiocephalus were an independent risk factor for HPS.