Synthesis , Spectroscopic Characterization and Antibacterial Assessment of Cadmium and Molybdenum Complexes of TcSal Mixed Ligand

The metal complexes of Cadmium and Molybdenum (II) were synthesized by refluxing equimolar mixtures of Tetracycline (Tc) as primary ligand and Salicylaldehyde (Sal) as a secondary ligand with M (II) salts (M = Cd & Mo) in ethanol media. The metallation of two exclusive ligands with Cd & Mo was monitored by the observation of change in color, surface tension, and conductivity. The stoichiometric ratio of the synthesized complexes was carried out using the physicochemical approach like elemental microanalysis (CHN), melting point, surface tension, conductivity measurement. The spectroscopic methods like FT-IR, 1H & 13C-NMR spectroscopy, UV/Vis, Mass spectrometry techniques. The surface structure of the complex was carried out through scanning electron microscopy (SEM). The thermodynamic and kinetic studies were carried out via TGA/DTA curves through which ∆E*, ∆H*, ∆S* & ∆G* parameters of several decomposition stages were evaluated by Coats-Redfern equation. The consequences of elemental microanalysis signify that these metal complexes of the mixed ligand are determined to have a 1:1 metal-to-ligand molar ratio. Molecular modeling gives geometry of the complex which was accomplished through Cs-Chem Office software program. The antibacterial activity study was done by KirbyBauer Paper disc diffusion techniques with the help of using S. aureus, E. coli, & P. aeruginosa clinical bacterial pathogens. All synthesized metal complexes showed good consequences in opposition to the selected clinical pathogenic bacterias.