P7‐34: Impact of pulmonary rehabilitation on pulmonary function measures, exercise capacity, quality of life and psychosocial parameters in patients with chronic obstructive pulmonary disease

Background and Aims: Reduced physical activity (PA) worsens the prognosis of patients with chronic obstructive pulmonary disease (COPD). However, the factors associated with the lower PA in COPD remain unexplicit. We measured the PAs of COPD patients to compare them with their clinical indicators. Methods: Twenty-three male outpatients with stable COPD who went to our hospital between October 2020 and May 2021 were enrolled with the written consent. We assessed their PA with a 3-dimension accelerometer and collected their clinical information at starting PA measurement. PAs were output as metabolic equivalents (METs) every 10 seconds. We calculated the average of daily sedentary time (the duration of intensity between 1.0 to 1.5 METs) and high-intensity PA (the duration of ≥3 METs). We estimated adjusted relationships between these indicators and the exercise tolerance or dyspnea using multiple linear regression analysis including age, the distance in 6 minutes walk test (6MWD), and modified medical research council dyspnea scale (mMRC) as explanatory variables. Results and Conclusions: The sedentary time showed a significant positive correlation with the mMRC; on the other hand, the high-intensity PA significantly correlated with 6MWD, an indicator of exercise tolerance. In mild to moderate COPD, both lowand high-intensity PA have been known to reduce the risk of COPD hospitalization. Our results implicate that we need two approaches in intervening PA of mild to moderate COPD patients: relieving dyspnea to reduce the sedentary time and improving exercise tolerance to increase high-intensity PAs for better COPD prognosis. P7-34 | Impact of pulmonary rehabilitation on pulmonary function measures, exercise capacity, quality of life and psychosocial parameters in patients with chronic obstructive pulmonary disease