Outpatient Microsurgical Breast Reconstruction

did not receive either preor postmastectomy radiation therapy. Patients with premastectomy radiation had higher rates of seroma (14.3% versus 0.2%; P < 0.001), minor infection (10.7% versus 1.2%; P = 0.009), implant loss (21.4% versus 3.4%; P = 0.001), and local recurrence (7.1% versus 1.0%; P = 0.049), when compared with those without radiation. Patients receiving premastectomy radiation also had a capsular contracture rate 3 times that of nonradiated patients (10.7% versus 3.2%; P = 0.075), although the difference was not significant. Patients with postmastectomy radiation had higher rates of major infection (8.4% versus 2.4%; P = 0.017), capsular contracture (19.7% versus 3.2%; P < 0.001), implant loss (9.9% versus 3.4%; P = 0.022), and local recurrence (5.6% versus 1.0%; P = 0.018), when compared with patients without radiation. Outcomes after prepectoral implant-based breast reconstruction were comparable between preand postmastectomy radiation therapy groups, respectively, with regard to major infection (7.1% versus 8.4%; P = 1.000), dehiscence (3.6% versus 1.4%; P = 0.488), major mastectomy skin flap necrosis (7.1% versus 2.8%; P = 0.317), capsular contracture (10.7% versus 19.7%; P = 0.382), implant loss (21.4% versus 9.9%; P = 0.184), and local recurrence (7.1% versus 5.6%; P = 1.000). However, patients with premastectomy radiation had a higher rate of seroma compared with those receiving postmastectomy radiation therapy (14.3% versus 0%; P = 0.005).