Characterization of a Novel FLT3 BiTE® Antibody Construct for the Treatment of Acute Myeloid Leukemia

Bettina Brauchle 1,2,† , Rebecca L. Goldstein 3,† , Christine M. Karbowski 4 , Anja Henn 5 , Chi-Ming Li 3 , Veit L. Bücklein 1,2 , Christina Krupka 1,2 , Michael C. Boyle 4 , Priya Koppikar 4 , Sascha Haubner 1,2 , Joachim Wahl 5 , Christoph Dahlhoff 5 , Tobias Raum 5 , Matthew J. Rardin 3 , Christine Sastri 3 , Dan A. Rock 3 , Michael von Bergwelt-Baildon 1,2,6 , Brendon Frank 3 , Klaus H. Metzeler 2,6 , Ryan Case 3 , Matthias Friedrich 5 , Mercedesz Balazs 3 , Karsten Spiekermann 2,6,7 , Angela Coxon 5 , Marion Subklewe 1,2,6,* , Tara Arvedson 3,*