Onset of Blast Crises in CML Patients in Treatment-Free Remission: Descriptive Analysis of 4 Cases

Stephanie Dulucq,Frédéric Bauduer,Jean-Michel Cayuela, Patrice Chevallier,Pascale Cony-Makhoul,Yannick Le Bris,Laurence Legros,Herve Maisonneuve,Lydia Roy,Francois-Xavier Mahon,Sandrine Hayette,Delphine Rea,Franck E. Nicolini

Blood（2021）

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Abstract

Aims: The onset of blast crisis (BC) in initially chronic phase (CP) CML patients that entered treatment-free remission (TFR) after TKI is an exceptional event, however, there is emerging evidence that this may occur in such patients (pts), although the pathogenesis remains unclear to date.

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Key words

blast crises,cml patients,treatment-free

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