Transcorneal Freezing in Aged Rabbits as a Platform for Evaluating Corneal Endothelial Cell Therapeutics.

This corneal endothelium injury platform is ideal for injury and therapeutic research as it can be rapidly performed, and has minimal impact on corneal thickness and intraocular pressure. Due to innate rabbit endothelial regrowth, it is vital to establish corneal endothelial recovery rate before evaluating therapeutics for efficacy in this model system.