A 6 pA rms 50 kHz-40 MHz Impedance Sensor for Source-Differential Flow Cytometry

This paper presents an electrical impedance-based cytometer for cell anaylsis applications. By adopting a 3-electrode layout and using a source-differential sensing scheme, baseline current is cancelled prior to the sensor front-end measurement circuit to achieve high sensitivity. To leverage the source-differential sensing scheme, a high-gain closed-loop impedance sensing circuit was designed to ...