Changes in CMR Parameters and Prediction of Cardiac Complications in Thalassemia Major: Fibrosis Tells Us More Than Iron

Alessia Pepe,Laura Pistoia,Pietro Giuliano,Nicola Giunta,Rosamaria Rosso,Alessandra Quota,Silvia Macchi,Aurelio Maggio,Giacomo Agliata,Stefania Renne,Vincenzo Positano,Antonella Meloni

Blood（2021）

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摘要

Introduction. Cardiovascular magnetic Resonance (CMR) has dramatically changed the clinical practice and improved the prognosis in thalassemia major (TM). This is the first study evaluating the predictive value of changes in CMR parameters (myocardial iron, function, and fibrosis) for cardiac complications in TM.

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thalassemia major,fibrosis,cardiac complications,iron

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