Dronabinol inhibits alveolar bone remodeling in tooth movement of rats

•Marijuana is one of the most widely used recreational drugs worldwide.•Previous research has only focused on the oral soft tissue effects of marijuana use.•Many prescription medications impact bone remodeling and orthodontic tooth movement.•First study demonstrating that dronabinol inhibits alveolar bone remodeling.•Routine use of marijuana may extend the length of orthodontic treatment.