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Chronic Glucocorticoids Consumption Triggers and Worsens Experimental Alzheimer's Disease-Like Pathology by Detrimental Immune Modulations.

Geoffrey Canet,Charleine Zussy,Célia Hernandez,Nathalie Chevallier,Nicola Marchi,Catherine Desrumaux,Laurent Givalois

Neuroendocrinology（2022）

Cited 4|Views10
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Abstract
This study unravels new functional outcomes identifying chronic CORT consumption as a main risk factor for AD and suggests that glucocorticoid-based therapies should be prescribed with caution in populations with AD risk.
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Key words
Alzheimer’s disease,Amyloid toxicity,Chronic glucocorticoids consumption,Memory deficits,Neuroinflammation
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