Metabolomics Work Flow and Analytics in Systems Biology
CURRENT MOLECULAR MEDICINE(2022)
Abstract
Metabolomics is an omics approach of systems biology that involves the development and assessment of large-scale, comprehensive biochemical analysis tools for metabolites in biological systems. This review describes the metabolomics workflow and provides an overview of current analytic tools used for the quantification of metabolic profiles. We explain analytic tools such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, ionization techniques, and approaches for data extraction and analysis.
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Key words
Biomarker, liquid chromatography, metabolomics, mass spectrometry, NMR spectroscopy, proteome
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