Increased circulating levels of High Mobility Group Box 1 (HMGB1) in acute-phase Chikungunya virus infection: Potential disease biomarker

Daniele C P Rocha, Thiara Manuelle Alves Souza,Priscila Conrado Guerra Nunes,Ronaldo Mohana-Borges,Marciano V Paes,Gabriel M C Guimarães, Juan C S Arcila,Iury Amâncio Paiva,Elzinandes Leal de Azeredo,Paulo Vieira Damasco,Luiz José de Souza,Flavia B Dos Santos,Diego Allonso

Journal of Clinical Virology（2022）

引用 6|浏览3

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摘要

•HMGB1 serum levels are increased during CHIKV infections.•HMGB1 serum levels keeps increased all over the acute-phase of the disease.•HMGB1 serum levels positively correlates with CHIKV viremia.•Previous DENV infection or YFV vaccination does not affect HMGB1 serum levels.

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Chikungunya infection,High Mobility Group Box 1,Disease biomarker

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