Development and validation of novel kit for quantification of SARS-CoV-2 antibodies on clinical samples

Sneha Kumari,Anoushka Raina,Dinesh Chandra,Nikita Gupta,Nikki Dey,Amit Kumar Bhardwaj,Archana Anthwal,Vikash C Mishra,Vimarsh Raina,Aseem K Tiwari,Rasika Setia, A S Bhatia

Journal of Virological Methods（2022）

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摘要

•A novel kit for quantification of SARS-CoV-2 antibodies on clinical samples was developed.•Kit was validated with known samples, blind trial, third party validation and WHO referral samples.•Comparison with FDA approved Surrogate virus neutralization kit was also done.•The kit showed sensitive and selective detection of antibody (IgG) against S1-RBD of SARS-CoV-2.

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关键词

SARS-CoV-2,Chimera,SOOCHAK,IgG,Clinical samples

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