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Cerebrospinal fluid liquid biopsies for medulloblastoma

Joan Seoane,Laura Escudero

NATURE REVIEWS CLINICAL ONCOLOGY（2021）

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Abstract
Cerebrospinal fluid liquid biopsies can enable the characterization and monitoring of medulloblastoma. The analysis of copy-number variations in circulating tumour DNA present in these samples can be used as a biomarker to determine the presence of measurable residual disease, and facilitate the optimal treatment and clinical management of patients with medulloblastoma.
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Key words
Cancer genetics,CNS cancer,Paediatric cancer,Tumour biomarkers,Medicine/Public Health,general,Oncology
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