Effects of the Lysine Methyltransferase Inhibitor AZ505 on Bone Metabolism.
Journal of bone metabolism(2021)
Abstract
The results indicate that AZ505 has a catabolic effect on bone metabolism in vivo despite its anabolic effect in bone cell cultures. The findings indicate that cell culture data should be extrapolated cautiously to in vivo outcomes for studying bone metabolism.
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Key words
Bone density,Methyltransferases,Osteoblast,Osteoclast
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