Automatic Estimation of Limbal Stem Cell Densities in Cultured Epithelial Cell Microscopy Imaging

Limbal stem cell deficiency (LSCD) is a progressive corneal disease that renders the corneal epithelium unable to repair itself, which can lead to the eventual loss of vision. Advances in technology have allowed for the growth of limbal stem cells ex-vivo for the purposes of transplantation. One method used to evaluate the quality of these cultivated cells is cell density, which is typically calcu...