Duo Shared Genomic Segment analysis identifies a genome-wide significant risk locus at 18q21.33 in myeloma pedigrees.
Journal of translational genetics and genomics(2021)
Abstract
Our results provide novel risk loci with segregating evidence from multiple HRPs and offer compelling targets and specific segment carriers to focus a future search for functional variants involved in inherited risk formyeloma.
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Key words
High-risk pedigrees,disease susceptibility,gene mapping,multiple myeloma
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