Genetic predisposition to Parkinson's disease and risk of cardio and cerebrovascular disease: a Mendelian randomization study

Mengmeng Wang,Zhizhong Zhang,Dandan Liu,Lei Ji,Shuangjiao Huang,Liping Cao,Ning Wei,Dan Ye,Yazhou Ma,Xuegan Lian

Parkinsonism & Related Disorders（2022）

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摘要

•This study showed that genetic predisposition to PD is associated with higher risk of IS and CES in European population.•In East Asian population, we found no evidence of causal effect of PD on the risk of IS and CAD.

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PD,IS,MI,MR,LAS,SVS,CES,CAD,GWAS,SNP,IPDGC,TOAST,CARDIoGRAMplusC4D,IVW,MR-PRESSO,LOO,ORs,CIs

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