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Partial EMT takes the lead in cancer metastasis

Jef Haerinck,Geert Berx

Developmental cell（2021）

Cited 12|Views3
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Abstract
In this issue of Developmental Cell, Lueuroond et al. developed a tracing system, using the uncharacterized early epithelial-mesenchymal transition (EMT)-marker Tenascin C, to monitor cells undergoing partial EMT during malignant mammary cancer progression. They find that partial, but not full, EMT contributes to metastasis and that full EMT contributes to chemoresistance.
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