Characteristics of hemodialysis patient with critical COVID-19
THERAPEUTIC APHERESIS AND DIALYSIS(2022)
Abstract
Introduction: The clinical course of hemodialysis patients with COVID-19 still remains unclear. Methods: Thirty-four hemodialysis patients were retrospectively enrolled. Patients were divided according to disease severity, and clinical symptoms and laboratory data at admission were compared. Results: The serum C-reactive protein (CRP) level, D-dimer level, and white blood cell (WBC) count were significantly higher in the group with critical disease than in the group with mild to severe disease (p = 0.005, p = 0.039, and p = 0.045). The serum CRP level exceeded 10 mg/dl within 7 days of clinical onset in all the cases with critical disease. Conclusion: Hemodialysis patients with COVID-19 who have elevated serum CRP and D-dimer levels, and an elevated WBC count at admission and patients with serum CRP levels exceeding 10 mg/dl before day 7 after clinical onset should be carefully monitored for possible progression to critical disease.
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Key words
COVID-19, C-reactive protein, D-dimer, hemodialysis, interferon lambda 3
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