Helminth-induced CD9+ B-cell subset alleviates obesity-associated inflammation via IL-10 production

Maining Li,Huiquan Wang,Yangyue Ni,Chen Li,Xuejun Xu,Hao Chang,Zhipeng Xu,Min Hou,Minjun Ji

International Journal for Parasitology（2022）

Cited 6|Views25

No score

Abstract

•Schistosome infection could expand regulatory B cells (Bregs) in mice.•CD19±CD9± B cells produced more IL-10 than conventional B10 cells.•Adoptive transfer of CD9± B cells from infected mice had the capacity to markedly alleviate obesity-related inflammation.•CD9± B cells induced by helminth infection play a role in regulation of host metabolic disorders through IL-10 production.

Translated text

Key words

Helminths,Regulatory B cell,CD9,Immunometabolism

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined