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Move over NAIP, DDX17 diversifies the NLRC4 inflammasome

Katherine C Barnett,Kaixin Liang,Jenny P-Y Ting

SCIENCE IMMUNOLOGY（2021）

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Abstract
DDX17 binds short interspersed nuclear element RNAs to nucleate a dual NLRC4/NLRP3 inflammasome, highlighting the emerging role of endogenous ligands in NLRC4 activation (see the related Research Article by Wang .).
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