Pyroptosis, and its Role in Central Nervous System Disease

Yingchao Hu,Bingwei Wang,Sheng Li,Shuo Yang

Journal of Molecular Biology（2022）

引用 29|浏览4

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摘要

•Pyroptosis is an inflammatory form of cell death executed by gasdermin proteins.•Pyroptosis is activated in an inflammasome-dependent or -independent manner.•Pyroptosis in different cells contribute to the development of neuroinflammation.•Pyroptosis is involved in CNS diseases and is a potential therapeutic target.

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关键词

gasdermins,inflammasomes,caspase,neuroinflammation,neurological diseases

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