Patterns and predictors of relapse in Merkel cell carcinoma: Results from a population-based study

Kurian Joseph,Justina Wong,Aswin Abraham,Julia Zebak,Anushree Patel,Aoife Jones Thachuthara,Umar Iqbal,Truong-Minh Pham,Anjali Menon,Sunita Ghosh,Heather Warkentin,John Walker, Naresh Jha,Salman Faruqi,Thomas G. Salopek,Michael Smylie

Radiotherapy and Oncology（2022）

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摘要

•Adjuvant radiotherapy (RT) improved locoregional control and recurrence free survival without impact on MCC-specific survival and overall survival.•Adjuvant RT may be avoided instage I patients with a clear margin of 1–2 cm after surgery and negative Sentinal Lymph Node Biopsy (SLNB), without high-risk factors.•Co-morbidity was independently associated with overall survival.

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关键词

Merkel cell carcinoma,Adjuvant radiotherapy,Co-morbidity,Sentinel lymph node biopsy

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