Molecular chaperone TRiC governs avian reovirus replication by protecting outer-capsid protein σC and inner core protein σA and non-structural protein σNS from ubiquitin- proteasome degradation

•TRiC stabilizes the outer-capsid protein σC, inner core protein σA, and the non-structural protein σNS of ARV.•TriC serves as a chaperone of viral proteins and prevents their degradation via the ubiquitin-proteasome pathway.•Inhibition of TRiC significantly reduced expression levels of σC, σA, and σNS proteins of ARV and virus yield.