Lack of association between seborrheic dermatitis and SARS-CoV-2 outcomes

Seborrheic dermatitis (SD) is a common form of dermatitis. Immune dysregulation is presumed to play a role in SD pathogenesis, with increased prevalence of SD in patients with older age, immunosuppression and neuropsychiatric disease. These characteristics have also been found to be associated with worse SARS-CoV-2 outcomes. Several pro-inflammatory cytokines associated with greater SARS-CoV-2 morbidity, e.g. interleukin-1, 6 and tumor necrosis factor-alpha, contribute to SD pathogenesis. A recent report of a severely ill SARS-CoV-2 patient developing SD suggests a possible associations between these two conditions. However, few studies examined potential associations between SD and SARS-CoV-2 outcomes. We investigated the relationship between SD and SARS-CoV-2 outcomes among adults with dermatologic disease.