Effects of clozapine and risperidone antipsychotic drugs on the expression of CACNA1C and behavioral changes in rat ‘Ketamine model of schizophrenia
Neuroscience Letters(2022)
摘要
•Long-term of high-dose risperidone did not affect expression of CACNA1C in hippocampus.•Long-term of high-dose Clozapine did not affect expression of CACNA1C in hippocampus.•Clozapine and risperidone could partially improve cognitive impairment in rats.
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关键词
Schizophrenia,Ketamine,Clozapine,Risperidone,Elevate plus maze,Social interaction,Open field
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