Applying Modified Small Bladder Patch-To-Bladder Double-Layer Sutures To Establish A Rat Renal Transplantation Model

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE(2021)

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摘要
Rationale: A modified, rat small bladder patch-to-bladder double-layer suture for urinary tract reconstruction was used to establish a rat kidney transplantation model, and the model was compared with the donor bladder patch-recipient bladder anastomosis method to determine its effect on the improved urinary tract reconstruction rat renal transplantation method. Methods: Rats were randomly divided into two groups. Group A: The donor, small bladder patch-recipient bladder mucosa seromuscular layer single-layer suture group (n=10). Group B: The donor bladder patch-recipient bladder double-layer suture group (n=11). The operation times and the urinary tract reconstruction complications were compared. Results: The urinary tract reconstruction times were 14.12 +/- 1.73 min in Group B and 10.16 +/- 1.19 min in Group A. The difference between the two groups was statistically significant (P<0.05). The incidence of urinary tract complications in Group A was 25%, and the incidence of urinary tract complications in Group B was 9.09%, and the difference between the two groups was statistically significant (P<0.05). Conclusion: The modified urinary tract reconstruction with small bladder-receptor bladder double-layer suture technique significantly reduces urinary tract complications compared with the traditional single-layer suture technique, but the urinary tract reconstruction time is longer than the traditional single-layer suture time. It can significantly reduce the possibility of urinary leakage and is a highly reliable reconstruction procedure.
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关键词
Rats, kidney transplantation, urinary tract reconstruction, double-layer sutures, bladder patches
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