Blood Transfusion-Induced Posterior Reversible Encephalopathy Syndrome With Periodic Sharp Wave Complexes, 14-3-3 Protein Elevation, And The Pulvinar Sign

A 52-year-old Japanese woman was admitted to our hospital with consciousness disturbance and convulsions at 10 days after transfusion with 10 U of blood due to severe anemia. Electroencephalography showed periodic sharp wave complexes, cerebrospinal fluid 14-3-3 protein levels were elevated, and brain magnetic resonance imaging demonstrated bilateral thalamic hyperintensity. These findings suggested Creutzfeldt-Jakob disease (CJD); however, her symptoms were resolved with antiepileptic and anti-hypertensive drugs. We herein report a case of posterior reversible encephalopathy syndrome that occurred after a blood transfusion who showed features compatible with CJD.